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Elon Musk was asked how long until there is regular travel to Mars. His answer was not about rockets. He said the threshold that actually matters is whether Mars survives if the ships from Earth stop coming. That means every input: air, food, fuel, spare parts, medicine. He compared it to a long sea voyage where the only thing missing is vitamin C. One missing item and the colony dies on schedule. The ships could stop for reasons that have nothing to do with Mars. A war. A decline. An asteroid. His line: civilisation on Earth can end with a bang or a whimper. That is insurance logic, and it is the honest way to describe the Mars plan. Every policy has a premium, a probability and a payout. The payout here is the survival of the species, so the premium is nearly impossible to argue against. The probability is the part nobody can price. Which creates a strange corporate problem. The premium gets paid by companies whose shareholders will not be the ones rescued if the policy ever pays out. SpaceX is private, so its investors signed up for that. A public company could not easily spend decades of free cash flow on a backup planet and explain it on a quarterly call. The other catch is that redundancy is only worth what you spend testing it. A city is not self-sustaining because the plan says so. It is self-sustaining the day the ships stop and everyone lives. So the number worth watching is not the landing date. It is the date Mars stops needing Earth. Nobody is selling a ticket to that.

Pharma firms closed biopharma buyouts worth over a hundred billion dollars in the first half of the year, racing to replace top selling medicines worth around $400 billion before patents expire. Leah Bennett of Concurrent explains

Pharma firms closed biopharma buyouts worth over a hundred billion dollars in the first half of the year, racing to replace top selling medicines worth around $400 billion before patents expire. Leah Bennett of Concurrent explains

A humanoid is a capital good on a scale that changes the constraint. It lengthens production and raises what labor and land can turn out, which is the abundance Elon is pointing at. A person supplies about 2,000 hours a year. A robot on a 168 hour week supplies about 8,700. His floor of 1 billion within 10 years, priced in the low 10,000s, equals about 4 billion full time equivalents against a world labor force of 3.5 billion. The 10 billion at 15 years is an order of magnitude past that. Robots building robots still require saving, because energy, materials, and machines have to be bid into that line. Expected abundance holds for ordinary wants which is what matters for people as consumers. Housing, food, care, and routine medicine get repriced toward energy and materials until a household’s budget stops being what limits them. An owner running 100s or 1,000s of agents earns the return on that capital stock, which is also how universal high income shows up as purchasing power. Money prices remain the way to allocate whatever is still scarce, that is energy, locations, raw materials. At least in the short term. Energy is the binding input, and settling more than one planet adds land, minerals, and generation beyond a single world. TLDR: (1) More energy. (2) Multiplanetary doesn’t hurt.

Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR. We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use. Read more:

Yesterday, on World Alzheimer’s Day, we were reminded of the importance of nutrition in supporting brain health and those impacted by Alzheimer’s disease. At Planet Harvest, we know that food is medicine. I’m proud to partner with @EliLillyandCo and @thrive to deliver 13,500 fresh food boxes—more than 200,000 pounds of nutritious fruits and vegetables—alongside brain health resources across 10 U.S. cities. Together with our local partners, we’re turning a shared commitment to healthier communities into meaningful, tangible support for thousands of families. I hope this effort inspires more partnerships that expand access to the resources people need to live healthier lives. 💪🥦🥕🍅🥒🍊🥑🍋📦 @PlanetHarvest1

📍Chinese Terms Unlocked: China's New "New Three" #NewThree# #intelligence# #robotic# #medicine# @CNYouthDaily @salahzhang @AmbassadeChine @consulat_de @ChenPingMFA @CGMeifangZhang @zhang_heqing @AmbXieFeng @xuejianosaka @ChineseEmbinAus @ChineseEmbinUK @EmbChina_RS @chinacgedi

Elon basically predicted the next revolution in medicine: “You can effectively think of the future of medicine as being digital” Much of traditional drug discovery has involved finding or screening molecules, testing them, and figuring out what they can do Synthetic RNA starts changing that model From discovering drugs by accident → programming treatments like software If we can understand exactly what biological instructions need to be written into RNA, medicine increasingly becomes something we can design for a specific problem And once we know what to program into synthetic RNA: “You can basically, cure almost anything” Medicine is becoming programmable