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ARTO long-term analysis Adding SBRT to abiraterone acetate + prednisone + ADT may improve outcomes in selected patients with oligometastatic CRPC. At 53-month median follow-up • OS: not reached vs 50 mo • HR 0.55; p=0.021 • bPFS: 44 vs 18 mo • rPFS: 44 vs 17 mo • 4-yr PC-specific survival: 86.6% vs 67.7% No new safety concerns were reported. @MicheleAquilano @alessiobruni @BarbaraJereczek @GabSimontacchi @PierluigiBonomo @ChadTangMD #ProstateCancer# #GUOncology# #SBRT# #Oncology#
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New in Advances in Radiation Oncology: Titanium vs Carbon/PEEK spinal implants in postoperative spine SBRT: a review of imaging, dosimetry, and clinical evidence. Key finding: Carbon/PEEK reduces CT artifact volume up to ~90% and cuts photon max dose perturbation from ~30% to ~5%; in protons, CTV underdose error drops from 17.3% to 4.1%, near implant-free levels. Why it matters: artifacts complicate contouring and dose calculation exactly where ablative dose meets spinal cord, and cleaner imaging helps detect recurrence earlier. Important caveat: clinical outcome data remain retrospective and limited; no direct contouring-accuracy comparisons exist, and Carbon/PEEK costs more. Bottom line: the dosimetric advantages are consistent and real, but improved local control is not yet proven. Randomized data (CarbonS trial) are coming. @ASTRO_org #RadOnc# #OncTwitter#
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Excited to share the results of the #ARTO# trial. After a median f-up of 53 months, Adding SBRT to abiraterone + ADT significantly improved overall survival (HR 0.55). @dicataldovanes1 @BarbaraJereczek @Ric_Campi @ChadTangMD @TheLancetOncol @ESTRO_RT
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How do we define the role of SBRT in HCC amidst many other available local modalities? Do we need a Ph III RCT with OS endpoint? Thoughts from @ldawsonmd, liver SBRT pioneer now s/p after decades of experience leading HCC trials.
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Can neo-adj RT ⚡️ restore response to ICI in PD-L1-neg ER+ breast cancer? #NeoCheckRay#: 3×8 Gy SBRT + anti-PD-L1 showed strong pCR signal in PD-L1 neg . On-treatment biopsies suggest TME reprogramming toward an immune-responsive state. @NatureMedicine ➡️
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Learn about NRG-GI012, a Ph3 RCT of IO +/- SBRT in HCC w Macrovascular Invasion! W the great Drs. @jen_wo_xrt (PI) & @ldawsonmd. Please enroll on this pragmatic RCT to help define the role of SBRT in a pt population w significant unmet need. Clips here, full video link below.
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#NEWSクランチ# !にて連載 #ChumToto# さんの「教えて先輩!ちゃむ相談室」に ゲストで #福田朱里# が登場させていただいています📢 アイドル愛や #ディアステージ# さんへの愛が炸裂しつつ、素敵な化学反応を感じる内容となっています💓 ぜひチェックしてください✨ #STU48#
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