PL Capital (@plcapital)
@plcapital
We back computing breakthroughs early.
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Gene therapies that teach neurons to quiet seizures. Non-invasive read/write across the whole brain. Brain implants placed in a 30-minute procedure without opening the skull. These are the bets that @JacquesCarolan is funding as a founding Program Director at @ARIA_research.
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A recent BCI landscape piece by @Bloomberg features five PLC Neurotech portfolio companies: @Merge, @paradromics, @PrecisionNeuro_ , @ScienceCorp_, and @synchroninc.
“The industry could be reaching an inflection point thanks to rapid advances in hardware and artificial intelligence models that can decode neural signals.”
We agree. We're long on the space for a reason.
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PLC Neurotech GP @juanbenet launched his new podcast with @maxhodak_ of @ScienceCorp_ ("one of the most cracked and genuine people in Silicon Valley" — @beffjezos).
From biohybrid neural interfaces that grow living neurons onto silicon, to PRIMA already restoring meaningful vision in AMD patients, to the rigorous engineering discipline required for atomic-level control and true frontier speed — this episode captures exactly why neurotech is one of the most important investment frontiers of our time.
At @plcapital, we believe the convergence of biology and computing will create entirely new protocols for intelligence and human capability.
Vertical integration, the "smartphone dividend," and a hiring bar centered on intrinsic urgency + judgment are all signals of the kind of organization that can actually move the needle in this space.
Watch the full conversation below 👇
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Excited to launch a new podcast dedicated to conversations on the future of neurotech, computing, intelligence, and more.
First guest: @maxhodak_ founder & CEO of @ScienceCorp_, which is building PRIMA, a retinal prosthetic that’s restoring meaningful vision for patients with blindness caused by age-related macular degeneration.
Science is also developing a biohybrid brain implant that grows living neurons directly onto a silicon chip, then interfaces that system with the cortex. The possibility space here is vast and new. Imagine growing new areas of the brain.
Sections
00:00 What counts as neurotech?
01:45 History of brain-computer interfaces and the smartphone dividend
07:25 PRIMA - How Science is restoring vision in blind patients
10:10 Why stimulating bipolar cells works when the optic nerve doesn't
30:30 Are we bottlenecked by biology or engineering?
32:40 Expanding the brain's bandwidth beyond 10 bits per second
37:00 Can we add new areas to the brain?
37:46 Biohybrid BCIs: neurons growing on a chip
39:20 What could neural augmentation look like?
01:13:20 How Science drives Fast R&D
01:44:00 How founders learn and level up
This is the kind of discussion I’m excited to explore on this podcast. Enjoy!
Full Episode 1 here and in links below.
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